Missense variant pathogenicity predictors generalize well across a range of function‐specific prediction challenges
نویسندگان
چکیده
منابع مشابه
Missense variant pathogenicity predictors generalize well across a range of function-specific prediction challenges.
The steady advances in machine learning and accumulation of biomedical data have contributed to the development of numerous computational models that assess the impact of missense variants. Different methods, however, operationalize impact differently. Two common tasks in this context are the prediction of the pathogenicity of variants and the prediction of their effects on a protein's function...
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ژورنال
عنوان ژورنال: Human Mutation
سال: 2017
ISSN: 1059-7794,1098-1004
DOI: 10.1002/humu.23258